Top level Function calls in Chrome Flame charts

I'm looking at a flame chart of my Angular application. I understand most of it, there are top level XHRs, SetTimeouts,Parse, GC, Script evaluation etc. But there are a few top level 'Function calls', (They seem to be coming from Zone.JS globalZoneAwareCallback.

火焰图

Any idea how functions get triggered at the top of the call stack like this?

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